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Cancer Biology Faculty

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Ahlquist, Paul G. (Molecular Virology, Oncology, Plant Pathology), Molecular mechanisms of viral replication, host interactions and oncogenesis

Alarid, Elaine T. (Oncology), Molecular mechanisms of steroid hormone action

Alexander, Caroline (Oncology), Mammary stem cells; mouse mammary tumor models; Wnt signaling; syndecan-1

Allen-Hoffmann, B. Lynn (Pathology and Laboratory Medicine), Keratinocytes; cancer biology; extracellular matrices

Bertics, Paul J. (Biomolecular Chemistry), Regulation of cell proliferation and function by growth factors, cytokines and bacterial toxins

Bradfield, Christopher A. (Oncology), Molecular biology of the PAS family of proteins

Bresnick, Emery H. (Pharmacology), Stem cell biology, molecular hematology, and vascular biology: from fundamental mechanisms to translational medicine

Bushman, Wade (Surgery/Urology), Developmental pathways in prostate cancer

Dove, William F. (Oncology and Medical Genetics), Colon cancer

Drinkwater, Norman R. (Oncology), Genetics and molecular biology of carcinogenesis

Friedl, Andreas (Pathology and Laboratory Medicine), Role of heparan sulfate proteoglycans in tumor-stroma interactions

Friesen, Paul D. (Molecular Virology, Biochemistry), Molecular biology of eukaryotic DNA viruses; regulation of gene expression; programmed cell death (apoptosis); retrotransposons

Fritsch, Michael K. (Pathology and Laboratory Medicine), Chromatin remodeling during early embryonic stem cell differentiation

Gould, Michael N. (Oncology), Molecular biology of mammary carcinogenesis

Griep, Anne E. (Anatomy), Genetic and molecular regulation of mouse eye development and disease

Halberg, Richard B. (Medicine), Tumor formation and progression in the gut: new concepts and novel targets for therapeutic intervention

Harari, Paul (Human Oncology), Examination of molecular targets that modulate growth characteristics of human squamous cell carcinomas

Hoffmann, F. Michael (Oncology and Medical Genetics), Drug discovery focused on the TGF-beta signaling pathway Smad proteins in pancreatic cancer, diabetic nephropathy and muscular dystrophy

Jarrard, David F. (Surgery/Urology), Genetic and epigenetic alterations in prostate cancer

Kalejta, Robert F. (Molecular Virology and Oncology), Cell cycle progression and DNA replication; viral manipulation of the cell cycle; HCMV replication and pathogenesis; Rb/E2F pathway; ubiquitin-mediated proteolysis; HCMV genetics

Keely, Patricia J. (Pharmacology), Understanding molecular mechanisms underlying breast cancer risk due to breast density

Kenney, Shannon C. (Medicine and Oncology), Understanding the molecular regulation and pathogenesis of the human herpesvirus, Epstein-Barr virus (EBV)

Kiessling, Laura L. (Biochemistry and Chemistry), Biomolecular recognition processes; the chemistry and biology of protein-saccharide interactions

Lambert, Paul F. (Oncology), Molecular genetics of papillomaviruses

Loeb, Daniel D. (Oncology), Molecular biology of the hepatitis B viruses

McNeel, Douglas G. (Medicine), Immunology of prostate cancer

Mertz, Janet E. (Oncology), Transcriptional regulation in DNA tumor viruses and breast cancer

Miyamoto, Shigeki (Pharmacology), Regulation of the transcription factor NF-kB as a model system to study cancer

Moser, Amy (Human Oncology), Cancer and developmental genetics of the mouse

Mosher, Deane F. (Medicine, Biomolecular Chemistry), Extracellular matrix in cell growth and development

Raines, Ronald T. (Biochemistry), Chemical biology, protein design and engineering, enzymology

Rapraeger, Alan C. (Pathology and Laboratory Medicine), Examining the mechanisms by which the syndecan family of cell surface receptors regulate cell growth, adhesion, and migration

Ross, Jeffrey (Oncology), Regulation of mRNA stability in mammalian cells

Sandgren, Eric (Pathobiological Sciences), Regulation of cell growth during tissue regeneration and carcinogenesis

Schuler, Linda A. (Comparative Biosciences), The role of prolactin in mammary cancer, its interactions with other hormones and growth factors in disease processes using cell culture and transgenic mouse models, and the control of prolactin receptor expression and processing in normal and tumor cells

Shull, James D. (Oncology), Cancer genetics, hormones and breast cancer, estrogen action

Striker, Robert T. (Medical Microbiology & Immunology and Medicine), Oncogenesis, pathogenesis, and pharmacotherapy of Hepatitis C Virus

Sugden, Bill (Oncology), Molecular biology of the human tumor virus, Epstein-Barr virus

Tibbetts, Randal S. (Pharmacology), Molecular mechanisms of genome surveillance and neurodegeneration

Weaver, Beth A. (Molecular Pharmacology), Chromosome segregation during mitosis; effects of chromosome missegregation on tumors

Xing, Yongna (Oncology), Cell signaling pathways related to cancer; structural biology; biochemistry; proteomics

Xu, Wei (Oncology), Epigenetic transcriptional control in breast cancer

Zhang, Jing (Oncology), Hematopoietic and leukemic stem cells; mouse models for hematopoietic malignancies; cytokine signaling